Images of elderberries11/30/2023 Cohort 1 contained 101 individuals with negative Covid-19 test results, whilst cohort 2 contained 122 individuals with positive results displaying mild symptoms or who were asymptomatic.īoth cohorts were randomised to receive either 3g daily of oral LCLT supplementation or a placebo over a period of 21 days, with measured endpoints including infection incidence in cohort 1 and disease progressions in cohort 2. The scientists conducted a randomised controlled trial utilising two cohorts of participants. Thus, the researchers sought to investigate the safety of daily supplementation with LC in those vulnerable to the COVID-19 infection or who have already tested positive, to determine its potential protective effect. Subsequent research has investigated the influence of LC on reducing viral infection risk, with studies noting that supplementation was able to inhibit hepatitis C and Covid infection of the lungs. These events have been noted to involve the upregulation of the ACE2 receptor a protein to which the COVID-19 spike protein (S protein) binds and enables entry into host cells. It is known that COVID-19 is characterised by significant inflammation, whereby cytokine storms can lead to organ failure. LC is responsible for the transportation of long-chain fatty acids into the mitochondria for oxidation, with previous studies highlighting its involvement in inflammatory pathway mediation by reducing inflammatory cytokines and oxidative stress. “In conclusion, our data suggest that LCLT supplementation may have coagulation modulating effects and result in clinical improvement in patients with COVID-19,” they emphasise. The ‘Nutrients’ published article highlights: “Our results showed that LCLT supplementation was safe and well tolerated, and may be protective, since we found a decrease in coagulation disturbance markers, as well as reduction in the severity of lung alterations when given to patients with mild COVID-19 (Cohort 2).” L carnitine L-tartrate (LCLT) is the salt form of the amino acid derivative L-carnitine (LC) and this study evaluated the use of the LCLT 'Carnipure' supplement. The gut-brain axis: Psychobiotic opportunity in 25 countriesįurther chest scans also revealed that the supplemented group showed significantly improved lung lesion improvement, when compared to the placebo groups, highlighting its potential to slow COVID-19 progression.Uncovering white spaces – Probiotics for a smooth menopause transition.Uncovering White Spaces – Probiotics for Pets.POSTbiotics – New Tools in Microbiome Modulation.After the pandemic: Business lessons and insights from 25 probiotic supplement e-markets.
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